The use of oral sodium phosphate products, like Fleet Phospho-soda, Visicol and OsmoPrep, to clear out the bowels before a colonoscopy or other medical procedure, have been associated with the development of a rare but serious form of kidney injury known as acute phosphate nephropathy.
The Fleet Phospho-soda attorneys at Dr Shezad Malik Law Firm are investigating potential Acute Phosphate Nephropathy lawsuits for patients who have been diagnosed with the kidney condition after using an over-the-counter Fleet Phospho-soda laxative at high doses for colonoscopy prep.
In most cases the kidney damage from Fleet Phospho-soda is permanent and may require dialysis treatment, a kidney transplant or even lead to death.
Acute Phosphate Nephropathy, which is sometimes referred to as Acute Nephrocalcinosis, is an acute kidney injury which can develop within a few hours or up to several days after use of Fleet Phospho-soda or other oral sodium phosphate products to clean the bowels before a colonoscopy or colon surgery.
The kidney injury is associated with deposits of calcium-phosphate crystals in the renal tubules that can permanently impair kidney function.
Bowel cleansing with Fleet Phospho-soda or oral sodium phosphate prescription medications cause acute phosphate nephropathy because they result in dehydration, decreased intravascular volume and hyperphosphatemia, which increase phosphate levels in the renal tubules.
The decreased intravascular volume stimulates reabsorption of water from the renal tubules, which further increases the concentration of phosphate levels in renal tubular fluid and causes precipitation of calcium-phosphate crystals in the kidney.
In December 2008, the FDA warned that two prescription oral sodium phosphate drugs, Visicol and OsmoPrep, would require “black box” warnings about the acute phosphate nephropathy side effects, which is the strongest warning that can be placed on a prescription medication.
The prescription drug makers were also required to develop a risk evaluation and mitigation strategy and to distribute a medication guide with their products so that patients are informed of the kidney injury risk. They also must conduct post-marketing clinical trials to further evaluate the extent of the risk.
The same day the FDA issued their alert, C.B. Fleet Co. issued a Fleet Phospho-soda recall for their over-the-counter oral sodium phosphate laxative, which they had been marketing at higher doses as a bowel prep.
As a result of the acute phosphate nephropathy problems, Fleet removed the product from the market and indicated that it may be reintroduced as a prescription product at a later date if approved by the FDA.
Potential Fleet Phospha-soda lawsuits are being reviewed by the acute phosphate nephropathy attorneys at Dr Shezad Malik Law Firm for patients throughout the United States who have developed kidney problems. All cases are reviewed on a contingency fee basis, which means that there are no fees or expenses unless a recovery is obtained.
If you or a family member has been personally injured because of the fault of someone else: by the use of dangerous drugs, bad products, or toxic injury etc then please contact the Fort Worth Texas Defective Drugs Product Liability Attorney Dr. Shezad Malik. For a no obligation, free case analysis, please call 817-255-4001 or Contact Me Online.
The Dr. Shezad Malik Law is currently evaluating and accepting Fleet Phospho-soda and Acute Phosphate Nephropathy side effects cases.