A dye used in MRI (magnetic resonance imaging) and MRA (magnetic resonance angiography) scans has been linked to a rare and potentially fatal skin disease in some users.
The problem stems from the metal gadolinium found in the dyes injected into some patients before MRI scans and all patients before MRA scans.
The disease is known as nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy (NSF/NFD), and appears to only occur in patients with kidney disease who undergo an MRI or MRA where a gadolinium-based dye is used.
These dyes, known as “contrast agents,” are commonly injected into patients shortly before they undergo MRI or MRA scans. MRI and MRA scans are frequently used as a non-invasive procedure for doctors to see inside the body to look for many problems, such as tumors, internal organ complications, clogged arteries, brain irregularities, and more.
The Food and Drug Administration (FDA) states in a public health advisory: “Patients with moderate to end-stage kidney disease who receive an MRI or MRA with a gadolinium-based contrast agent may get NSF/NFD, which is debilitating and may cause death.”
The FDA later asked for a boxed warning to be included in all gadolinium-based contrast agents (GBCAs) to warn of the potential of NSF in some patients. The FDA then asked the manufacturers to include a black box warning (the strongest warning possible) on all gadolinium-based products. The warning notes that these dyes may increase the risk of potentially fatal side-effects in patients with certain kidney and liver conditions.
The International Center for Nephrogenic Fibrosing Dermopathy Research describes the symptoms of NSF/NFD as, “Swelling and tightening of the skin, usually limited to the extremities, but sometimes involving the trunk. Severely affected patients may be unable to walk, or fully extend the joints of their arms, hands, legs, and feet.” NSF/NFD may develop over the course of several weeks.
The skin’s texture may also change to a wood-like consistency or feel like an orange peel. Accompanying these symptoms are sensations of burning, itching, and severe sharp pains in specific areas. Deep “bone pain” of the hips and ribs has also been reported. Severe cases can be fatal.
Our law firm is actively investigating cases of patients administered a gadolinium-based contrast dye who later suffered from nephrogenic systemic fibrosis or nephrogenic fibrosing dermopathy (NSF/NFD). We want to help. Call us today.
If you or a family member has been personally injured because of the fault of someone else: by the use of dangerous drugs, bad products, or toxic injury etc then please contact the Fort Worth Texas Defective Drugs Product Liability Attorney Dr. Shezad Malik. For a no obligation, free case analysis, please call 817-255-4001 or Contact Me Online.
The Dr. Shezad Malik Law is currently evaluating and accepting Gadolinium-based contrast dye cases who later suffered from Nephrogenic Systemic Fibrosis Side Effects.